How to Start Outlook in Safe Mode Using the Outlook Shortcut

To open Outlook in safe mode, press and hold the Ctrl key, then select the Outlook shortcut. In the warning dialog box that appears, confirm that you want to open Outlook in safe mode by selecting Yes

Screenshot of Safe Mode Confirmation window. 

Click OK

Outlook will now Open and ask for your password, this is the same as your windows login

Enter your Password and Click ok

Now Close outlook and reopen normally.

Outlook should function properly now.